Detection and Correction of Hypokalemia in Patients with Refractory Chronic Heart Failure

Abstrak

Treatment of heart failure (HF) is important in modern cardiology. One of the chronic heart problems in patients is the circulatory system. Due to the violation of neurohumoral regulation of blood circulation system in patients, the expansion function of peripheral blood vessels changes and the total resistance of peripheral blood vessels increases. Because of this, the ventricles of the heart are forced to increase their tension before contraction and after contraction. According to the conclusions of the World Health Organization, the incidence rate of diseases of the cardiovascular system takes the first place among the general morbidity and mortality rates. In 6-10% of cases, one of the reasons for hospital admission is the irregular intake of powerful diuretics and acute decompensation of CHF with hypokalemia. CHF was detected in more patients. In addition, every year more than 1,000 patients have CHF symptoms.  As a result of the decrease in the pumping function of the heart in the body, excessive retention of water in the small and large blood circulation is detected, it has been proven to recommend diuretic drugs to patients with CHF. Causes inadequate blood circulation in the organs and tissues, initially at times of slight physical exertion, and later at rest.  Disruption of neurohumoral mechanisms in the pathogenesis of CHF causes salt and water retention in the body. Water retention in the body, which in turn increases the amount of circulating plasma, and as a result, the end diastolic pressure in the left ventricle increases, leads to the development of heart failure [14,15]. In the initial stages of CHF, the main compensatory mechanism is the outflow of water and salts from the body. An increase in the amount of circulating blood leads to an increase in venous blood flow to the heart, which causes a temporary increase in left ventricular stroke volume
Aldosterone causes the body to retain water and sodium. Therefore, these neuro-humorous shifts initially have a compensatory nature, and at the next stages, they become pathological.

Kata Kunci