MULTIFORM EXUDATIVE ERYTHEMA OF THE ORAL MUCOSA: DIAGNOSIS AND COMPREHENSIVE TREATMENT

Abstrak

Objective: This study aims to improve the diagnosis and comprehensive treatment of multiform exudative erythema (MEE) in patients through a developed treatment algorithm, evaluating both subjective and objective criteria of the oral mucosa and local humoral immunity. Method: A total of 81 patients with MEE were treated according to a developed treatment protocol, with 30 patients in a comparison group receiving traditional therapy. Patient assessments included clinical examinations, immunological testing (s-IgA, IL-6, phagocytic index), and dental quality-of-life indicators using the OHIP-14-RU questionnaire. The main group received the newly developed therapeutic algorithm, while the comparison group received traditional treatments. Results: The main group showed significant improvements in pain reduction, lesion healing, and oral mucosa condition compared to the comparison group. The OHIP-14-RU scores improved by 8 points in the main group, indicating enhanced quality of life. Novelty: The study introduces a new therapeutic-hygienic algorithm for MEE treatment, which results in faster healing, improved clinical and immunological parameters, and a significant improvement in oral health-related quality of life.

Kata Kunci