Kuchimova Ch. A.
Jurnal: International Journal of Integrative and Modern Medicine
ISSN: 2995-5319
Volume: 3, Issue: 11
Tanggal Terbit: 27 November 2025
Chronic depressive disorders represent one of the most challenging clinical entities in contemporary psychiatry, characterized by persistent depressive symptoms lasting two years or more, with significant implications for patient functioning and quality of life. The complexity of these conditions extends beyond their prolonged duration to encompass intricate diagnostic considerations, treatment resistance patterns, and variable prognostic outcomes that significantly impact both individual patients and healthcare systems globally.